Development of uterine sarcoma after tamoxifen treatment for breast cancer: report of four cases

@article{Yldrm2004DevelopmentOU,
  title={Development of uterine sarcoma after tamoxifen treatment for breast cancer: report of four cases},
  author={Y. Yıldırım and M. Inal and M. Sancı and T. Mit and M. Polat and Ş. Tınar},
  journal={International Journal of Gynecologic Cancer},
  year={2004},
  volume={15},
  pages={1239 - 1242}
}
Tamoxifen (TAM) is widely used in the treatment of breast cancer, and its paradoxical effects on female genital system are well known. During the past 10 years, many descriptions of nonepithelial uterine malignancies related to long-term TAM usage have been reported in the literature. Four uterine sarcoma patients who had history of TAM usage for previous breast cancer are presented in this study. The mean time of exposure to TAM was 6 (range 3–11) years, and the mean cumulative dose of drug… Expand

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