Development of tolerance to the activating action of morphine, amphetamine, and alcohol on the positive reinforcement system in rats

Cases of polynarcomania the taking of a combination of drugs causing euphoria, and, if need be, the rep lacement of one such drug by another [8], known in cl inical p rac t ice suggest that the effects of these drugs a r e rea l i zed by common, including neurochemical , b ra in mechan isms . This is confirmed, in par t icu lar , by data in the l i t e ra… CONTINUE READING