Development of tolerance to the ACTH-releasing effects of beta-endorphin.

Abstract

Acute intracisternal injection of human beta-endorphin results in increased plasma concentration of adrenocorticotropic hormone (ACTH). Repeated injections of beta-endorphin are associated with the development of tolerance with regard to this ACTH-stimulating effect. 

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Cite this paper

@article{Loon1978DevelopmentOT, title={Development of tolerance to the ACTH-releasing effects of beta-endorphin.}, author={Gunther van Loon and Errol B De Souza}, journal={Research communications in chemical pathology and pharmacology}, year={1978}, volume={22 1}, pages={203-4} }