Development of tissue inflammation accompanied by NLRP3 inflammasome activation in rabbits infected with Treponema pallidum strain Nichols

@inproceedings{Lin2018DevelopmentOT,
  title={Development of tissue inflammation accompanied by NLRP3 inflammasome activation in rabbits infected with Treponema pallidum strain Nichols},
  author={Li-Rong Lin and Yao Xiao and Wei Liu and Yu-Yan Chen and Xiao-Zhen Zhu and Zheng-Xiang Gao and Kun Gao and Man-li Tong and Hui-lin Zhang and Shu-lian Li and Hui-ling Lin and Wen-Dong Li and Xian-Ming Liang and Yong Lin and Li-li Liu and Tian-Ci Yang},
  booktitle={BMC Infectious Diseases},
  year={2018}
}
BackgroundThe inflammasome responses in Treponema pallidum infection have been poorly understood to date. This study aimed to investigate the expression of the nucleotide-binding leucine-rich receptor protein 3 (NLRP3) inflammasome in the development of tissue inflammation in rabbits infected with T. pallidum.MethodsForty-five rabbits were randomly assigned to a blank group or an infection group, and the latter was divided into no benzathine penicillin G (BPG) and BPG treatment subgroups… CONTINUE READING
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