Development of the pharyngeal arches

@article{Graham2003DevelopmentOT,
  title={Development of the pharyngeal arches},
  author={Anthony Graham},
  journal={American Journal of Medical Genetics Part A},
  year={2003},
  volume={119A}
}
  • A. Graham
  • Published 15 June 2003
  • Medicine
  • American Journal of Medical Genetics Part A
The oro‐pharyngeal apparatus has its origin in a series of bulges that is found on the lateral surface of the embryonic head, the pharyngeal arches. The development of the pharyngeal arches is complex involving a number of disparate embryonic cell types: ectoderm, endoderm, neural crest and mesoderm, whose development must be co‐ordinated to generate the functional adult apparatus. In the past, most studies have emphasised the role played by the neural crest, which generates the skeletal… 
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References

SHOWING 1-10 OF 49 REFERENCES
Pharyngeal arch patterning in the absence of neural crest
Induction of the epibranchial placodes.
TLDR
This work answers the long standing question regarding the induction of the epibranchial placodes, and represents the first elucidation of an inductive mechanism, and a molecular effector, underlying the formation of any primary sensory neurons in higher vertebrates.
Segment and cell type lineage restrictions during pharyngeal arch development in the zebrafish embryo.
TLDR
It is suggested that arch precursors may be specified as to their eventual fates before the major morphogenetic movements that form the arch primordia, as in the fashion of vertebrate rhombomeres or segmental lineage compartments in Drosophila.
The endoderm plays an important role in patterning the segmented pharyngeal region in zebrafish (Danio rerio).
TLDR
The results of this analysis suggest that the segmentation of the endoderm occurs without signaling from neural crest cells but that tissue interactions between the mesendoderm and the Neural crest cells are required for the segmental appearance of the neural crest-derived cartilages in the pharyngeal arches.
Homeotic transformation of branchial arch identity after Hoxa2 overexpression.
TLDR
Hoxa2 appears to exert its effect during differentiation of the cartilage elements in the branchial arches, rather than during crest migration, implying that pattern is determined quite late in development, whereas the neural crest appears to contain some patterning information, it needs to read cues from the environment to form a coordinated pattern.
sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development.
TLDR
The results support a model for dorsoventral patterning of the gnathostome pharyngeal arches in which Et-1 in the environment of the postmigratory cranial neural crest specifies the lower jaw and other ventral arch fates.
The embryonic origins of avian cephalic and cervical muscles and associated connective tissues.
  • D. Noden
  • Biology
    The American journal of anatomy
  • 1983
TLDR
These results indicate that muscles associated with branchial arch skeletal structures are derived from paraxial mesoderm, as are all other voluntary muscles in the vertebrate embryo, and theories of vertebrate ontogeny and phylogeny based in part on proposed unique features of branchiomeric muscles must be critically reappraised.
Head morphogenesis in embryonic avian chimeras: evidence for a segmental pattern in the ectoderm corresponding to the neuromeres.
TLDR
It seems that not only is the neural crest patterned according to its rhombomeric origin but that the superficial ectoderm covering the branchial arches may be part of a larger developmental unit that includes the entire neurectoderm, i.e., the neural tube and the Neural crest.
Development of thymus, parathyroids, and ultimo-branchial bodies in NMRI and nude mice.
TLDR
Morphometric analysis shows that the volume of the parathyroids is the same in both strains of mice at each stage of development; nor does their microscopic appearance differ; thus, mutation in the Nude mouse does not affect the development of theParathyroid from the third pouch, even though the first anomalies in thedevelopment of the thymus are observed at the precise moment at which the par Kathyroid primordium appears.
...
1
2
3
4
5
...