Development of the neuromuscular junction

  title={Development of the neuromuscular junction},
  author={V. Witzemann},
  journal={Cell and Tissue Research},
  • V. Witzemann
  • Published 2006
  • Biology, Medicine
  • Cell and Tissue Research
  • The differentiation of the neuromuscular junction is a multistep process requiring coordinated interactions between nerve terminals and muscle. Although innervation is not needed for muscle production, the formation of nerve-muscle contacts, intramuscular nerve branching, and neuronal survival require reciprocal signals from nerve and muscle to regulate the formation of synapses. Following the production of muscle fibers, clusters of acetylcholine receptors (AChRs) are concentrated in the… CONTINUE READING
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