Development of the major pathways for neurite outgrowth in the chick hindlimb.

@article{Tosney1985DevelopmentOT,
  title={Development of the major pathways for neurite outgrowth in the chick hindlimb.},
  author={Kathryn W. Tosney and Lynn T. Landmesser},
  journal={Developmental biology},
  year={1985},
  volume={109 1},
  pages={193-214}
}
To elucidate mechanisms that may control development of the gross anatomical nerve pattern, motoneuron outgrowth into the chick hindlimb was examined using orthograde labeling, scanning and transmission electron microscopy, and Alcian blue staining. Results show that growth cones are not guided by contact with oriented extracellular fibrils, aligned mesenchyme cells, the myotome, or the vasculature. Pathways are not delineated by cell-free space or channels of lower cell density; however… CONTINUE READING

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