Development of the asymmetric human

  title={Development of the asymmetric human},
  author={Lewis Wolpert},
  journal={European Review},
  pages={97 - 103}
  • L. Wolpert
  • Published 22 August 2005
  • Biology
  • European Review
Symmetry across the midline is present in many animals, together with the left/right asymmetry of several organs, such as the heart in vertebrates. The development of such asymmetries during embryonic development requires first the specification of the midline and then specification of left/right. One model proposes the transfer of molecular asymmetry to the multicellular level. Nodal expression on the left side in mammals and chicks is a key event, and is due to the release of calcium on the… 
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Sequential transfer of left-right information during vertebrate embryo development.
Different strategies for midline formation in bilaterians
The evolutionary emergence of the bilateral body plan and the central nervous system required the establishment of a midline organizer, indicating that midline formation had a crucial role in the diversification of higher organisms.
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Principles of Development (Oxford
  • 2002
The development of handedness.
Right Hand, Left Hand (Weidenfeld)
  • 2002