Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies.

@article{Greving2014DevelopmentOT,
  title={Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies.},
  author={Jacoba P. Greving and Marieke J. H. Wermer and Robert J Brown and Akio Morita and Seppo Juvela and Masahiro Yonekura and Toshihiro Ishibashi and James C. Torner and Takeo Nakayama and Gabri{\"e}l J E Rinkel and Ale Algra},
  journal={The Lancet. Neurology},
  year={2014},
  volume={13 1},
  pages={59-66}
}
BACKGROUND The decision of whether to treat incidental intracranial saccular aneurysms is complicated by limitations in current knowledge of their natural history. We combined individual patient data from prospective cohort studies to determine predictors of aneurysm rupture and to construct a risk prediction chart to estimate 5-year aneurysm rupture risk by risk factor status. METHODS We did a systematic review and pooled analysis of individual patient data from 8382 participants in six… CONTINUE READING
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