Development of the Human True Vocal Fold: Depth of Cell Layers and Quantifying Cell Types within the Lamina Propria

@article{Boseley2006DevelopmentOT,
  title={Development of the Human True Vocal Fold: Depth of Cell Layers and Quantifying Cell Types within the Lamina Propria},
  author={Mark E. Boseley and Christopher J Hartnick},
  journal={Annals of Otology, Rhinology \& Laryngology},
  year={2006},
  volume={115},
  pages={784 - 788}
}
Objectives: We sought to further describe the development of the 3-layered human vocal fold in children and to quantify macrophage and myofibroblast concentrations in each layer. Methods: We used an optical analysis software package to examine 8 longitudinally sectioned human vocal folds that had been fixed in formalin (ages 2 days to 14 years). Results: The 2-day-old vocal fold contained only a monolayer of cells. This became a bilayer by 5 months, and a trilayer began to become evident by 7… 
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