Development of the GENIPOL European flounder (Platichthys flesus) microarray and determination of temporal transcriptional responses to cadmium at low dose.

@article{Williams2006DevelopmentOT,
  title={Development of the GENIPOL European flounder (Platichthys flesus) microarray and determination of temporal transcriptional responses to cadmium at low dose.},
  author={Tim D. Williams and Amer M. Diab and Stephen G. George and Rita E Godfrey and Victoria S Sabine and Ana Conesa and Steven D Minchin and Phil C Watts and James Kevin Chipman},
  journal={Environmental science & technology},
  year={2006},
  volume={40 20},
  pages={6479-88}
}
We have constructed a high density, 13 270-clone cDNA array for the sentinel fish species European flounder (Platichthys flesus), combining clones from suppressive subtractive hybridization and a liver cDNA library; DNA sequences of 5211 clones were determined. Fish were treated by single intraperitoneal injection with 50 micrograms cadmium chloride per kilogram body weight, a dose relevant to environmental exposures, and hepatic gene expression changes were determined at 1, 2, 4, 8, and 16… CONTINUE READING
32 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

Similar Papers

Loading similar papers…