Development of the AG68L strain of Newcastle disease vaccine. (1) Modification of the existing AG68L vaccine by clone purification and its subsequent testing.


After preliminary work had shown that the Newcastle disease vaccinal strain AG68L had considerable potential as a lentogenic vaccine for administration in the drinking water, it was studied for viral homogeneity and purified by plaque picking and cell culture passage. The fifth passage of a small plaque was used to immunise birds. Its performance was… (More)


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