Development of steroid signaling pathways during primordial follicle formation in the human fetal ovary.

@article{Fowler2011DevelopmentOS,
  title={Development of steroid signaling pathways during primordial follicle formation in the human fetal ovary.},
  author={Paul A. Fowler and Richard A. Anderson and Philippa T K Saunders and Hazel L. Kinnell and James Ian Mason and Dean B. Evans and Siladitya Bhattacharya and Samantha Flannigan and Stephen Franks and Ana Cec{\'i}lia Ferreira Monteiro and Peter O'Shaughnessy},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2011},
  volume={96 6},
  pages={1754-62}
}
CONTEXT Ovarian primordial follicle formation is critical for subsequent human female fertility. It is likely that steroid, and especially estrogen, signaling is required for this process, but details of the pathways involved are currently lacking. OBJECTIVE The aim was to identify and characterize key members of the steroid-signaling pathway expressed in the second trimester human fetal ovary. DESIGN We conducted an observational study of the female fetus, quantifying and localizing… CONTINUE READING
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