Development of specific anti-thymosin beta 10 antipeptide antibodies for application in immunochemical techniques.

@article{Leondiadis1996DevelopmentOS,
  title={Development of specific anti-thymosin beta 10 antipeptide antibodies for application in immunochemical techniques.},
  author={Leondios Leondiadis and Evangelia Livaniou and Irene Vassiliadou and Nikolas Ferderigos and Dionyssis S. Ithakissios and Gregory P. Evangelatos},
  journal={Peptides},
  year={1996},
  volume={17 7},
  pages={1091-6}
}
We present theoretical and experimental data necessary for raising specific antibodies for thymosin beta 10, a 43-amino acid residues peptide occurring in human tissues. We postulate that thymosin beta 10 contains three major antigenic determinants (residues 2-8, 17-25, and 35-41). For antibody development, we synthesized the N-terminal fragment thymosin beta 10(1-16) as well as the C-terminal fragments thymosin beta 10(31-43) and thymosin beta 10(38-43), due to their putative antigenic… CONTINUE READING

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