Development of solid self-emulsifying drug delivery systems: preparation techniques and dosage forms.

  title={Development of solid self-emulsifying drug delivery systems: preparation techniques and dosage forms.},
  author={Bo Tang and Gang Cheng and Jian-Chun Gu and Cai-Hong Xu},
  journal={Drug discovery today},
  volume={13 13-14},
Approximately 40% of new chemical entities exhibit poor aqueous solubility and present a major challenge to modern drug delivery system, because of their low bioavailability. Self-emulsifying drug delivery systems (SEDDS) are usually used to improve the bioavailability of hydrophobic drugs. Conventional SEDDS, however, are mostly prepared in a liquid form, which can produce some disadvantages. Accordingly, solid SEDDS (S-SEDDS), prepared by solidification of liquid/semisolid self-emulsifying… CONTINUE READING

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