Development of semi-separated co-culture system of sympathetic neuron and cardiomyocyte

Rat superior cervical ganglion (SCG) neurons and ventricular myocytes (VMs) were co-cultured in chambers made of polydimethylsyloxane. The chambers were placed on a microelectrode-array (MEA) substrate and connected with a pathway. 24 hours after dissemination of the VMs, neuntes of the SCG neurons outgrew through the pathway and reached the VMs… CONTINUE READING