Development of selective adsorbent for free-hemoglobin.

  title={Development of selective adsorbent for free-hemoglobin.},
  author={Takayuki Tsuchiya and Hideki Kawanishi and Mineo Sugiyama and Fujiichi Yoshimoto},
  journal={Biomaterials, artificial cells, and artificial organs},
  volume={18 4},
It is well-known that acute renal failure is often caused by hemolysis. Its possible causes may be free-hemoglobin (F-Hb), stroma freed from destroyed red blood cell, and their combined action. Especially, a great amount of F-Hb is liable to flow out during extracorporeal circulation. The plasma fractionation using a membrane has so far been applied to remove F-Hb (1). The molecular weight of F-Hb of 68,000 which is nearly equal to that of albumin has made it still difficult to separate F-Hb… CONTINUE READING
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