Development of romiplostim for the treatment of patients with chronic immune thrombocytopenia: from bench to bedside.

@article{Molineux2010DevelopmentOR,
  title={Development of romiplostim for the treatment of patients with chronic immune thrombocytopenia: from bench to bedside.},
  author={Graham Molineux and Adrian Newland},
  journal={British journal of haematology},
  year={2010},
  volume={150 1},
  pages={9-20}
}
Immune thrombocytopenia (ITP) is an autoimmune disorder characterised by abnormally low platelet counts (<100 x 10(9)/l), purpura, and bleeding episodes, and can be categorised in three phases: newly-diagnosed, persistent, and chronic. As many patients become refractory to standard treatments (corticosteroids, danazol, azathioprine, splenectomy), there is an urgent need for alternative treatments. The successful isolation and cloning of thrombopoietin (TPO) in the mid-1990s and identification… CONTINUE READING
14 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…