Development of real-time RT-PCR for evaluation of JEV clearance during purification of HPV type 16 L1 virus-like particles.

@article{Jeong2003DevelopmentOR,
  title={Development of real-time RT-PCR for evaluation of JEV clearance during purification of HPV type 16 L1 virus-like particles.},
  author={Hye-Sung Jeong and Jin-Ho Shin and Young-Nam Park and Jung-Yun Choi and Young-Lim Kim and Byoung-Guk Kim and Seung-Rel Ryu and Sun-Young Baek and Seok-Ho Lee and Sue-Nie Park},
  journal={Biologicals : journal of the International Association of Biological Standardization},
  year={2003},
  volume={31 3},
  pages={223-9}
}
Insect cell culture has greatly increased in part due to the widespread use of insect virus-based vectors for efficient expression of foreign proteins. Insect cells such as Sf9 cells are susceptible to arboviruses which may pose a safety concern by adventitious introduction during the production process. The objective of this study was to establish… CONTINUE READING