Development of quinolone-resistant strains of Escherichia coli in stools of patients with cirrhosis undergoing norfloxacin prophylaxis: clinical consequences.

@article{Aparicio1999DevelopmentOQ,
  title={Development of quinolone-resistant strains of Escherichia coli in stools of patients with cirrhosis undergoing norfloxacin prophylaxis: clinical consequences.},
  author={Jos{\'e} Ram{\'o}n Aparicio and Jos{\'e} Such and Sonia Pascual and Antonio L. Lagarda Arroyo and Joaqu{\'i}n Plazas and Eva Girona and Ana Gutierrez and F de Vera and Jos{\'e} Mar{\'i}a Palaz{\'o}n and Fernando Carnicer and Miguel P{\'e}rez-Mateo},
  journal={Journal of hepatology},
  year={1999},
  volume={31 2},
  pages={
          277-83
        }
}
BACKGROUND/AIM Norfloxacin prophylaxis decreases the incidence of bacterial infections in high-risk cirrhotic patients, but may promote the development of quinolone-resistant gram-negative bacteria in stools, and eventually lead to infections due to these bacteria. The aim of the study was to evaluate the prevalence of quinolone-resistant strains of E. coli in stools on admission, and the characteristics of any nosocomial infections. METHODS Eighty-three consecutively hospitalized cirrhotic… CONTINUE READING

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