Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.

@article{Alonzo2010DevelopmentOP,
  title={Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.},
  author={Eric S. Alonzo and Rachel A. Gottschalk and Joy R Das and Takeshi Egawa and Robin M Hobbs and Pier Paolo Pandolfi and Pablo Punal Pereira and Kim E Nichols and Gary A Koretzky and Martha S Jordan and Derek B Sant'Angelo},
  journal={Journal of immunology},
  year={2010},
  volume={184 3},
  pages={1268-79}
}
The broad-complex tramtrack and bric a brac-zinc finger transcriptional regulator (BTB-ZF), promyelocytic leukemia zinc finger (PLZF), was recently shown to control the development of the characteristic innate T cell phenotype and effector functions of NK T cells. Interestingly, the ectopic expression of PLZF was shown to push conventional T cells into an activated state that seems to be proinflammatory. The factors that control the normal expression of PLZF in lymphocytes are unknown. In this… CONTINUE READING
Highly Influential
This paper has highly influenced a number of papers. REVIEW HIGHLY INFLUENTIAL CITATIONS