Development of primary central nervous system lymphoma associated with human immunodeficiency virus and JC virus infection.

@article{Kawakami2014DevelopmentOP,
  title={Development of primary central nervous system lymphoma associated with human immunodeficiency virus and JC virus infection.},
  author={Toru Kawakami and Kaoko Sakai and Yuto Mimura and Yasushi Senoo and Yukio Hirabayashi and Hideyuki Nakazawa and Hiroshi Koshihara and Kenya Oguchi and Yo-ichi Takei and Shinji Ohara and Nobuaki Watanabe and Kou Nakazawa and Kiyomitsu Oyanagi and Kiyoshi Kitano},
  journal={Journal of clinical and experimental hematopathology : JCEH},
  year={2014},
  volume={54 3},
  pages={211-7}
}
We report here a case of a 37-year-old man with human immunodeficiency virus (HIV) infection followed by JC virus (JCV) infection and primary central nervous system lymphoma (PCNSL). The patient had been infected with HIV type 1 due to blood products for hemophilia A during infancy. He had progression of nervous symptoms and was diagnosed with progressive multifocal leukoencephalopathy (PML) clinically at the age of 36, when his CD4-positive lymphocyte counts ranged between 350 and 450/μl. Oral… CONTINUE READING