Development of porous spherical hydroxyapatite granules: application towards protein delivery.

@article{Paul1999DevelopmentOP,
  title={Development of porous spherical hydroxyapatite granules: application towards protein delivery.},
  author={Willi Paul and Chandra Prakash Sharma},
  journal={Journal of materials science. Materials in medicine},
  year={1999},
  volume={10 7},
  pages={383-8}
}
A new method for the preparation of porous spherical hydroxyapatite granules is reported. It may be clinically applied towards orthopaedic or maxillofacial surgery as fillers or packing materials, and as biological chromatography supports. Its application towards delivery of macromolecules or protein drugs is discussed utilizing human serum albumin (HSA) as a model protein. 

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