Development of porous chitosan/tripolyphosphate scaffolds with tunable uncross-linking primary amine content for bone tissue engineering.

The primary amine along the chitosan backbone plays a key role in biomedical applications. Although chitosan-based porous scaffolds have been widely used in tissue engineering, it remains very challenging to regulate uncross-linking primary amine content (CN) in scaffolds in order to realize particular mechanical and biological properties. In the present… CONTINUE READING