Development of poly(N-isopropylacrylamide)/alginate copolymer hydrogel-grafted fabrics embedding of berberine nanosuspension for the infected wound treatment

@article{Xu2014DevelopmentOP,
  title={Development of poly(N-isopropylacrylamide)/alginate copolymer hydrogel-grafted fabrics embedding of berberine nanosuspension for the infected wound treatment},
  author={He Xu and Xu-dong Yuan and Bao-de Shen and J. Han and Qing-yuan Lv and Ling Dai and Ming-Gui Lin and Chao Yu and Jin-xia Bai and H. Yuan},
  journal={Journal of Biomaterials Applications},
  year={2014},
  volume={28},
  pages={1376 - 1385}
}
In the present study, a novel hydrogel-grafted fabrics embedding of berberine nanosuspension was developed for the treatment of infected wound. Hydrogel-grafted fabric was prepared by graft copolymerization of N-isopropylacrylamide and alginate using ceric ammonium nitrate as initiator. Berberine nanosuspension was prepared and embedded in the hydrogel-grafted fabrics to achieve sustained drug release. The prepared hydrogel-grafted fabrics embedding of berberine nanosuspension was characterized… Expand
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