Development of parasagittal zonation in the rat cerebellar cortex: MabQ113 antigenic bands are created postnatally by the suppression of antigen expression in a subset of Purkinje cells.

@article{Leclerc1988DevelopmentOP,
  title={Development of parasagittal zonation in the rat cerebellar cortex: MabQ113 antigenic bands are created postnatally by the suppression of antigen expression in a subset of Purkinje cells.},
  author={Nicole Leclerc and Claude Gravel and Richard B. Hawkes},
  journal={The Journal of comparative neurology},
  year={1988},
  volume={273 3},
  pages={399-420}
}
Monoclonal antibody mabQ113 recognizes a polypeptide antigen that, in the adult cerebellum, is confined to a subset of Purkinje cells that are clustered together to form parasagittal bands interposed by similar nonimmunoreactive bands. The Purkinje cell compartments are congruent with bands of climbing fibers projecting from subregions of the inferior olivary complex (IOC). The array of mabQ113 parasagittal bands appears late in the development of the cortex. Weak mabQ113 immunoreactivity is… CONTINUE READING

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