Development of outward potassium currents in inner and outer hair cells from the embryonic mouse cochlea.

@article{Helyer2005DevelopmentOO,
  title={Development of outward potassium currents in inner and outer hair cells from the embryonic mouse cochlea.},
  author={Richard J Helyer and Helen J. Kennedy and D. A. L. Davies and Matthew C. Holley and Corn{\'e} J Kros},
  journal={Audiology & neuro-otology},
  year={2005},
  volume={10 1},
  pages={22-34}
}
We recorded K(+) currents in inner (IHCs) and outer (OHCs) hair cells from mice at embryonic days 16 and 18 and on the day of birth (PO) to characterize their early physiological differentiation. In both cell types, outward currents increased in size during late embryonic development, in cells situated in both the apical and basal coils of the cochlea. Currents increased up to six-fold, with current density increasing four-fold. Currents in basal cells were generally larger than in the apex… CONTINUE READING

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