Development of oral vaccines to stimulate mucosal and systemic immunity: barriers and novel strategies.

@article{Shalaby1995DevelopmentOO,
  title={Development of oral vaccines to stimulate mucosal and systemic immunity: barriers and novel strategies.},
  author={W S Shalaby},
  journal={Clinical immunology and immunopathology},
  year={1995},
  volume={74 2},
  pages={127-34}
}
  • W S Shalaby
  • Published 1995 in Clinical immunology and immunopathology
Many questions regarding the induction of mucosal and humoral immunity through oral vaccination exist. Efficacy is dependent on the physicochemical properties of the antigen, the gastrointestinal environment, the presence of adjuvants, and the mode of delivery. Understanding how these factors interrelate will be critical to the development of new oral vaccines. A number of approaches are currently being studied to enhance the immune response. These include chemical conjugation, immunization… CONTINUE READING

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