Development of novel CH223191-based antagonists of the aryl hydrocarbon receptor.

@article{Choi2012DevelopmentON,
  title={Development of novel CH223191-based antagonists of the aryl hydrocarbon receptor.},
  author={Eun Young Choi and Hyosung Lee and R. W. Cameron Dingle and Kyung Bo Kim and Hollie I. Swanson},
  journal={Molecular pharmacology},
  year={2012},
  volume={81 1},
  pages={3-11}
}
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that regulates genes involved in drug/xenobiotic metabolism, cell cycle progression, cell fate determination, immune function, and inflammatory response. Increasing evidence that AHR plays a role in the pathophysiology of a number of human disease states is driving the need for improved pharmacological tools to be used for understanding the in vivo impact of AHR modulation. In this study, we have characterized and used… CONTINUE READING
11 Citations
18 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 18 references

Similar Papers

Loading similar papers…