Development of new inbred transgenic strains of rats with LacZ or GFP.

  title={Development of new inbred transgenic strains of rats with LacZ or GFP.},
  author={Hirokazu Inoue and Ichiro Ohsawa and Takashi Murakami and Atsushi Kimura and Yoji Hakamata and Yuki Sato and Takashi Kaneko and Masafumi Takahashi and Takashi Okada and Keiya Ozawa and Jeremy S. Francis and Paola Leone and Eiji Kobayashi},
  journal={Biochemical and biophysical research communications},
  volume={329 1},
The ideal goal of regeneration medicine is to restore form and function to damaged tissues. While stem cell transplantation is considered a promising therapeutic approach, knowing the fate of transplanted cells using appropriate markers is essential. We developed new inbred transgenic rat strains with lacZ and GFP based on the transgenic (Tg) animal technique in rats. These Tg animals expressed most of their marker genes ubiquitously, compared to previous Tg rats. Immunological antigenicity… CONTINUE READING
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