Development of natural tolerance and induced desensitization in cow's milk allergy.

  title={Development of natural tolerance and induced desensitization in cow's milk allergy.},
  author={Emma Merike Savilahti},
  journal={Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology},
  volume={24 2},
Cow's milk allergy (CMA) affects 2-3% of infants. It resolves in the great majority spontaneously during childhood. CMA encompasses a spectrum of clinical and immunologic characteristics. Non-IgE-mediated allergy typically resolves earlier than IgE-mediated allergy. The most documented prognostic characteristic is that intense-specific IgE response predicts persistence of CMA. Low serum levels of cow's milk (CM)-specific IgG4 are also associated with persistent CMA. Natural development of… CONTINUE READING
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