Development of intestinal ischemia/reperfusion-induced acute kidney injury in rats with or without chronic kidney disease: Cytokine/chemokine response and effect of α-melanocyte-stimulating hormone

@inproceedings{Skott2014DevelopmentOI,
  title={Development of intestinal ischemia/reperfusion-induced acute kidney injury in rats with or without chronic kidney disease: Cytokine/chemokine response and effect of α-melanocyte-stimulating hormone},
  author={Martin Skott and Rikke N\orregaard and Hanne Birke-S\orensen and Johan Palmfeldt and T Chong-Suk KwoN and Thomas E. N. Jonassen and J\orgen Fr\oki{\ae}r and S\oren Nielsen},
  booktitle={Kidney research and clinical practice},
  year={2014}
}
BACKGROUND The primary aim of the study was to investigate the cytokine/chemokine response in the kidney, lung, and liver following acute kidney injury (AKI). The secondary aim was to test whether α-melanocyte-stimulating hormone (α-MSH) could prevent a reduction in organ function, and attenuate the inflammatory cytokine/chemokine response within the kidney, lung, and liver following AKI in rats with or without preexisting chronic kidney disease (CKD). METHODS A two-stage animal model, in… CONTINUE READING

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