Development of improved vaccines against whooping cough: current status.
@article{Marzouqi2010DevelopmentOI,
title={Development of improved vaccines against whooping cough: current status.},
author={Ibrahim Marzouqi and Peter Richmond and Scott R Fry and John D. Wetherall and Trilochan Kanwaljit Singh Mukkur},
journal={Human vaccines},
year={2010},
volume={6 7},
pages={
543-53
}
}
Prior to the introduction of killed whole cell pertussis vaccine [wP] in the 1940s, whooping cough was a major cause of infant death worldwide. Widespread vaccination of children with this vaccine caused a significant reduction in mortality. However in the 1990s and now more recently, there has been a resurgence of pertussis in several countries even in populations previously vaccinated with an acellular pertussis vaccine [aP]. In this review, we describe the epidemiology of whooping cough, the… CONTINUE READING