Development of human liver UDP-glucuronosyltransferases.

@article{Burchell1989DevelopmentOH,
  title={Development of human liver UDP-glucuronosyltransferases.},
  author={Brian Burchell and Michael W. H. Coughtrie and Mandy Jackson and D M Harding and Sylvie Fournel-Gigleux and Jonathan Leakey and Robert Hume},
  journal={Developmental pharmacology and therapeutics},
  year={1989},
  volume={13 2-4},
  pages={70-7}
}
The development of multiple UDPGT activities towards eight substrates has been studied in fetal term and adult post-mortem (less than 5 h after death) liver samples. Most fetal and term liver activities were less than 14% of adult values, except that towards 5-hydroxytryptamine which was present in fetal and term liver at adult levels. The majority of UDPGT activities develop to adult levels within 10-20 weeks postnatally, and even premature (30 weeks) which survive for up to 10 weeks will… CONTINUE READING

From This Paper

Topics from this paper.
26 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

Similar Papers

Loading similar papers…