Development of glial cells in the cerebral wall of ferrets: Direct tracing of their transformation from radial glia into astrocytes
@article{Voigt1989DevelopmentOG, title={Development of glial cells in the cerebral wall of ferrets: Direct tracing of their transformation from radial glia into astrocytes}, author={Thomas B. Voigt}, journal={Journal of Comparative Neurology}, year={1989}, volume={289} }
Coronal sections of the cerebral wall from developing ferrets (newborn to adult) were double‐stained with antibodies to vimentin and glial fibrillary acidic protein (GFAP). At birth, the dominant glial population was radial glia and these cells labeled only for vimentin. A small population of immature astrocytes in the cortical plate was double labeled for GFAP and vimentin. In successive days, the number of vimentin‐positive radial glia gradually decreased and they disappeared entirely at…
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References
SHOWING 1-10 OF 27 REFERENCES
Transition between immature radial glia and mature astrocytes studied with a monoclonal antibody to vimentin.
- BiologyBrain research
- 1984
Radial glia in the human fetal cerebrum: A combined golgi, immunofluorescent and electron microscopic study
- Medicine, BiologyBrain Research
- 1978
Arrested proliferation of radial glial cells during midgestation in rhesus monkey
- BiologyNature
- 1979
Whether radial glial cells in the fetal monkey cerebrum undergo cell division after attaining their radial configuration is investigated to ensure a faithful mapping of the proliferative ventricular surface upon the expanding and convoluted cerebral cortex of primates, including man.
Immunocytochemical demonstration of vimentin in astrocytes and ependymal cells of developing and adult mouse nervous system
- BiologyThe Journal of cell biology
- 1981
The results show that vimentin and GFA protein coexist in one cell type not only in primary cultures in vitro but also in the intact tissue in situ.
Immunoperoxidase localization of glial fibrillary acidic protein in radial glial cells and astrocytes of the developing rhesus monkey brain
- BiologyThe Journal of comparative neurology
- 1980
PAP immunohistochemical staining, utilizing a specific antibody to the glial fibrillary acidic protein (GFA), was employed to analyze gliogenesis in the central nervous system of rhesus monkeys ranging in age from embryonic day 38 to birth and through the second postnatal month.
Astrocyte‐specific protein and neuroglial differentiation. An immunofluorescence study with antibodies to the glial fibrillary acidic protein
- BiologyThe Journal of comparative neurology
- 1974
In the mature brain and spinal cord the distribution and appearance of neuroglia as observed with immunofluorescence were similar to those described by Weigert ('95) using his method for astrocytic fibers.
Mode of cell migration to the superficial layers of fetal monkey neocortex
- BiologyThe Journal of comparative neurology
- 1972
Golgi and electronmicroscopic methods were used to define the shapes and intercellular relationships of cells migrating from their sites of origin near the ventricular surface across the intermediate…
Postnatal development of interstitial (subplate) cells in the white matter of the temporal cortex of kittens: A correlated Golgi and electron microscopic study
- BiologyThe Journal of comparative neurology
- 1988
It is concluded that 1C belong to the population of early generated subplate cells which may have a transient function involved in certain morphogenetic events during the development of the cortical plate.
Localization of vimentin, the nonspecific intermediate filament protein, in embryonal glia and in early differentiating neurons. In vivo and in vitro immunofluorescence study of the rat embryo with vimentin and neurofilament antisera.
- BiologyDevelopmental biology
- 1982
Initial expression of neurofilaments and vimentin in the central and peripheral nervous system of the mouse embryo in vivo
- BiologyThe Journal of neuroscience : the official journal of the Society for Neuroscience
- 1984
The appearance of neurofilaments (NFs) and vimentin (Vim) in the nervous system of the mouse embryo was documented using immunohistochemical techniques and correlates extremely well with neurofibrillar differentiation and with the expression of adrenergic neurotransmitter properties.