Development of focal glomerulosclerosis after unilateral nephrectomy in infant rats

@article{Celsi1987DevelopmentOF,
  title={Development of focal glomerulosclerosis after unilateral nephrectomy in infant rats},
  author={Gianni E Celsi and Sven-Olof Bohman and Anita C. Aperia},
  journal={Pediatric Nephrology},
  year={1987},
  volume={1},
  pages={290-296}
}
Rats unilaterally nephrectomized in infancy (Nx5) or in adulthood (Nx55) and fed a normal (21%) protein diet were studied at 2, 3 and 6 months after surgery with regard to glomerular filtration rate (GFR) and the development of both albuminuria and focal glomerulosclerosis (FGS) in the remnant kidney. Nx rats were compared with sham-operated animals (S) of corresponding age. The incidence of FGS never exceeded 1.4% in S rats. In Nx5 rats the incidence of FGS was not increased at 2 and 3 months… CONTINUE READING
18 Citations
27 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 27 references

Renal size and function of the remaining kidney in patients with renal agenesis and patients nephrectomized in childhood for hydronephrosis (abstract)

  • I Wikstad, L Larsson, P Herin, A Aperia
  • Pediatr Nephrol 1 : C 27. Received June
  • 1986
1 Excerpt

Inhibition of tromboxane synthesis amelio296 rates the progressive kidney disease of rats with subtotal renal ablation

  • ML Purkerson, JH Joist, J Yaates, A Valdes, A Morrison, S Klahr
  • Proc Natl Acad Sci USA
  • 1985
1 Excerpt

Urinary albumin exretion in renal transplant donors

  • BM Chavers, AF Michael, D Welland, JS Najarian, SM Mauer
  • Am J Surg
  • 1985
1 Excerpt

Similar Papers

Loading similar papers…