Development of fatty acid-producing Corynebacterium glutamicum strains.

@article{Takeno2013DevelopmentOF,
  title={Development of fatty acid-producing Corynebacterium glutamicum strains.},
  author={Seiki Takeno and Manami Takasaki and Akinobu Urabayashi and Akinori Mimura and Tetsuhiro Muramatsu and Satoshi Mitsuhashi and Masato Ikeda},
  journal={Applied and environmental microbiology},
  year={2013},
  volume={79 21},
  pages={6776-83}
}
To date, no information has been made available on the genetic traits that lead to increased carbon flow into the fatty acid biosynthetic pathway of Corynebacterium glutamicum. To develop basic technologies for engineering, we employed an approach that begins by isolating a fatty acid-secreting mutant without depending on mutagenic treatment. This was followed by genome analysis to characterize its genetic background. The selection of spontaneous mutants resistant to the palmitic acid ester… CONTINUE READING
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