Development of fast atom bombardment mass spectral methods for the identification of carcinogen-nucleoside adducts.


An analytical strategy using fast atom bombardment (FAB) ionization and tandem mass spectrometry has been developed to determine the molecular weight and major fragment ions, and to provide limited structural characterization of low picomole levels of carcinogen-nucleoside adducts. This strategy consists of three main components: (1) the sensitivity for… (More)
DOI: 10.1016/1044-0305(92)87064-6