Development of compartmental models in stable-isotope experiments: application to lipid metabolism.

@article{Pont1998DevelopmentOC,
  title={Development of compartmental models in stable-isotope experiments: application to lipid metabolism.},
  author={Fr{\'e}d{\'e}ric Pont and Laurence Duvillard and B{\'e}n{\'e}dicte Verges and Philippe Gambert},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1998},
  volume={18 6},
  pages={853-60}
}
Kinetic experiments are of great importance in lipid research because they further the understanding of lipid metabolism in vivo and help to explain the physiopathology of lipid disorders in humans. At present, due to species specificity, no valid animal model can efficiently replace a study in humans to explore lipid metabolism, and the use of radioactive tracers is restricted in humans. Thus, stable-isotope tracer kinetic studies have become an important component of research programs to… CONTINUE READING
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