Development of chronic and acute golden Syrian hamster infection models with Leptospira borgpetersenii serovar Hardjo.

@article{Zuerner2012DevelopmentOC,
  title={Development of chronic and acute golden Syrian hamster infection models with Leptospira borgpetersenii serovar Hardjo.},
  author={Richard L. Zuerner and David P. Alt and Mitchell V Palmer},
  journal={Veterinary pathology},
  year={2012},
  volume={49 2},
  pages={403-11}
}
The golden Syrian hamster (Mesocricetus auratus) is frequently used as a model to study virulence for several Leptospira species. Onset of an acute lethal infection following inoculation with several pathogenic Leptospira species has been widely adopted for pathogenesis studies. An important exception is the outcome following inoculation of hamsters with live L. borgpetersenii serovar Hardjo, the primary cause of bovine leptospirosis and a cause of human infections. Typically, inoculation of… CONTINUE READING

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