Development of cholinergic inhibitory capacities in the hyperthyroid mouse.

  title={Development of cholinergic inhibitory capacities in the hyperthyroid mouse.},
  author={James M Murphy and Z. Michael Nagy},
  journal={Pharmacology, biochemistry, and behavior},
  volume={5 4},
The ontogeny of behavioral arousal and inhibition, as measured by spontaneous locomotor activity, was compared in four experiments for controls and mice injected with thyroxine as neonates. Mice treated with thyroxine at 1-3 days of age had higher activity levels at 10-15 days of age than controls, suggesting potentiation of arousal systems by the hormone treatment. Although thyroxine-accelerated development had no reliable effect upon the age at which peak activity occurred, scopolamine… CONTINUE READING

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