Development of chitosan membrane using non-toxic crosslinkers for potential wound dressing applications

  title={Development of chitosan membrane using non-toxic crosslinkers for potential wound dressing applications},
  author={B. Moghadas and A. Solouk and Davoud Sadeghi},
  journal={Polymer Bulletin},
  pages={1 - 11}
  • B. Moghadas, A. Solouk, Davoud Sadeghi
  • Published 2020
  • Chemistry
  • Polymer Bulletin
  • There is a myriad of ways to crosslink hydrogel wound dressings; however, they require additional steps to remove the residue of the crosslinking agents, or their byproducts in biological environments are toxic. In this study, we studied and characterized the crosslinking of the chitosan hydrogels by various dicarboxylic acids, including oxalic acid, adipic acid, and sebacic acid under vacuum at 90 °C. The concentrations of the crosslinkers in the crosslinked hydrogels are tolerable for the… CONTINUE READING

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