Development of chitosan/heparin nanoparticle-encapsulated cytolethal distending toxin for gastric cancer therapy.


AIM The aim of this work was to develop pH-responsive nanoparticles encapsulating CdtB and to demonstrate that these particles represent a potential therapeutic agent for gastric cancer. MATERIALS & METHODS Chitosan/heparin nanoparticle-encapsulated CdtB was prepared and the delivery efficiency was monitored by confocal laser scanning microscopy. The… (More)
DOI: 10.2217/nnm.13.54


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