Development of candidate rotavirus vaccines derived from neonatal strains in India.

@article{Glass2005DevelopmentOC,
  title={Development of candidate rotavirus vaccines derived from neonatal strains in India.},
  author={Roger I Glass and Maharaj Kishan Bhan and Pratima Ray and Rajiv Bahl and Umesh Parashar and Harry E. Greenberg and C. Durga Rao and Nita Bhandari and Yvonne Maldonado and Richard L. Ward and David I Bernstein and Jon R. Gentsch},
  journal={The Journal of infectious diseases},
  year={2005},
  volume={192 Suppl 1},
  pages={
          S30-5
        }
}
The need for a rotavirus vaccine in India is based on the enormous burden associated with the >100,000 deaths due to rotavirus diarrhea that occur annually among Indian children. Two rotavirus strains identified during nosocomial outbreaks of rotavirus infection in New Delhi and Bangalore, India, more than a decade ago are being developed as live oral vaccines. Infected newborns had no symptoms, shed virus for up to 2 weeks after infection, mounted a robust immune response, and demonstrated… CONTINUE READING

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