Development of calcium release mechanisms during starfish oocyte maturation.

@article{Chiba1990DevelopmentOC,
  title={Development of calcium release mechanisms during starfish oocyte maturation.},
  author={Kazuyoshi Chiba and Raymond T. Kado and Laurinda A Jaffe},
  journal={Developmental biology},
  year={1990},
  volume={140 2},
  pages={300-6}
}
In response to the maturation-inducing hormone 1-methyladenine, starfish oocytes acquire increased sensitivity to sperm and inositol trisphosphate (InsP3), stimuli that cause a release of calcium from intracellular stores and a rise in intracellular free calcium. In the immature oocyte, the calcium release in response to 10 sperm entries is less than that seen with a single sperm entry in the mature egg. Likewise, the sensitivity to injected InsP3 is less in the immature oocyte. Approximately… CONTINUE READING