Development of bioactive and biodegradable chitosan-based injectable systems containing bioactive glass nanoparticles.

@article{Couto2009DevelopmentOB,
  title={Development of bioactive and biodegradable chitosan-based injectable systems containing bioactive glass nanoparticles.},
  author={Daniela S Couto and Zhongkui Hong and Jo{\~a}o F Mano},
  journal={Acta biomaterialia},
  year={2009},
  volume={5 1},
  pages={115-23}
}
There is increasing interest in the development of new tissue engineering strategies to deliver cells and bioactive agents encapsulated in a biodegradable matrix through minimally invasive procedures. The present work proposes to combine chitosan-beta-glycerophosphate salt formulations with bioactive glass nanoparticles in order to conceive novel injectable thermo-responsive hydrogels for orthopaedic reconstructive and regenerative medicine applications. The initial rheological properties and… CONTINUE READING

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