Development of benzo [ 1 , 4 ] oxazines as biofilm inhibitors and dispersal agents against Vibrio cholerae †

@inproceedings{Warner2014DevelopmentOB,
  title={Development of benzo [ 1 , 4 ] oxazines as biofilm inhibitors and dispersal agents against Vibrio cholerae †},
  author={Christopher J. A. Warner and Andrew Tai-Ann Cheng and Fitnat H. Yildiz and Roger G. Linington},
  year={2014}
}
Bacterial biofilms are surface associated bacterial communities of sessile cells encased in a matrix of polysaccharides, extracellular DNA and proteins. Such biofilms are of significant concern in nosocomial infections, where it is attributed to over $1 billion in increased hospital costs per annum in the US alone. Unlike cells in the planktonic state, bacterial biofilms do not exert their antimicrobial resistance through mutation or acquisition of resistance functions by horizontal gene… CONTINUE READING