Development of bactericidal antibody during Branhamella catarrhalis infection.

  title={Development of bactericidal antibody during Branhamella catarrhalis infection.},
  author={Annelise Sabine Chapman and Daniel M. Musher and Steinn J{\'o}nsson and Jill E. Clarridge and Richard J. Wallace},
  journal={The Journal of infectious diseases},
  volume={151 5},
The recent observation that Branhamella catarrhalis may cause a variety of infections in humans has stimulated interest in human host defenses against this organism. We encountered 21 patients with B. catarrhalis infection: seven with pneumonia, 13 with a purulent exacerbation of chronic bronchitis, and one with purulent sinusitis. Normal human serum (NHS) demonstrated no bactericidal activity against 20 of the 21 isolates. In contrast, 7 of 19 acute and 18 of 20 convalescent sera demonstrated… CONTINUE READING


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