Development of bacterial vectors for tumor-targeted gene therapy.


Gene therapy holds great promise for the treatment of cancer. The success of the strategy relies on effective gene transfer into tumor microenvironments. Although a variety of gene delivery vehicles, such as viral vectors, has been developed, most of them suffer from some limitations, including inadequate tumor targeting, inefficient gene transfer, and… (More)
DOI: 10.1007/978-1-59745-561-9_7


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