Development of antral follicles in human cryopreserved ovarian tissue following xenografting.

@article{Gook2001DevelopmentOA,
  title={Development of antral follicles in human cryopreserved ovarian tissue following xenografting.},
  author={Debra A. Gook and B A McCully and David H. Edgar and John McBain},
  journal={Human reproduction},
  year={2001},
  volume={16 3},
  pages={417-22}
}
This study reports the first gross morphological and histological evidence of antral follicle development in human ovarian tissue following cryopreservation. Human ovarian tissue was cryopreserved using propanediol and sucrose and grafted under the renal capsule of bilaterally oophorectomized severe combined immunodeficient (SCID) mice. Follicles at all stages of development were observed in the grafted tissue whereas, prior to grafting, only primary and primordial follicles were present… CONTINUE READING
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